Interdisciplinary Laureats 2024

Nathalie Delgehyr (IBENS) & Julie Plastino (LPENS) & Ayako Yamada (ENS-Department of Chemistry) - Changes in internal nuclear dynamics induced by perinuclear mechanical forces I Mechanical forces are important for fate determination. Our project focuses on how direct actin-based forces affect nuclear internal organization and the consequences of the reorganization on neural stem cell fate.

Nicolas Delsuc (ENS-Department of Chemistry) & Olivier Espeli (CIRB) - Antibacterial treatment by hyperthermia using metal carbonyls-functionalized silica particles: towards a nanopasteurization process. I Antibiotic resistance is a major threat to public health in the 21st century. NanoPasteurization explores a novel way of combating pathogenic bacteria using non-toxic radiations to, in a way, burn off the bacteria and their protective biofilms, or, in pasteurizing from the inside.

Chris Bowler (IBENS) & Romain Koszul (Institut Pasteur) - Diatom zombies: Revealing 3D genome structure of ancient resting spores to investigate millennial-scale adaptations to a changing environment I The project investigates ancient diatom spores, revived from Antarctic sediments, to understand how they survive extreme dormancy. By analyzing the 3D structure of their genome, we will reveal how they remain in a state of suspended animation over millennia.